Many people with diabetes turn to cannabis to treat their neuropathic pain. But recent research reveals that the endocannabinoid system is implicated in the regulation of insulin production and blood glucose. The majority of studies indicate that endocannabinoids in the pancreas decrease insulin secretion, but other studies have shown the opposite. As a Johns Hopkins researcher notes, “the exact nature of the effects of endocannabinoids on insulin secretion require rigorous study examining both acute and long-term effects at physiologically relevant doses employing both whole animal and clinically relevant models such as human islets in vitro and explanted in vivo, in rodent models of diabetes.” What is clear is that the regulatory role of endocannabinoids in many of the body’s most complex physiologic systems suggests a target for cannabinoid-based therapies.

Kim W, et al. 2011. Cannabinoids Inhibit Insulin Receptor Signaling in Pancreatic {beta}-Cells. Diabetes. Feb 23.
Doyle ME. 2011. The role of the endocannabinoid system in islet biology. Curr Opin Endocrinol Diabetes Obes. Feb 9.

One Response to Cannabinoids May Regulate Diabetes

  1. […] Cannabinoids May Regulate Diabetes By admin On November 14, 2011 · Leave a Comment […]

Leave a Reply

Your email address will not be published. Required fields are marked *