Scientists at Florida State University investigated the role of the endocannabinoid system in endometriosis, a disease common in women that is associated with severe pain and is difficult to treat. Using a rat model, they discovered CB1 cannabinoid receptors throughout the abnormal growths that characterize endometriosis. Blocking those CB1 receptors increased pain sensitivity, while stimulating them reduced it. They conclude that the endocannabinoid system plays a role in the development of the abnormal growths and pain associated with endometriosis, suggesting cannabinoids may provide “badly-needed new treatments.”

Dmitrieva N,et al. 2010. Endocannabinoid involvement in endometriosis. Pain. Dec;151(3):703-10.

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